Scientific evaluation, supervision and safety monitoring of medicines in the EU. Issues qualification opinions on novel methodologies including clinical outcome assessments.
Visit EMAStandard MS disability staging scale.
Primary disability progression endpoint in MS clinical trials
EMA Guideline on clinical investigation of medicinal products for the treatment of multiple sclerosisAD trials cognitive endpoint (11- and 13-item forms).
Co-primary cognitive endpoint in Alzheimer's disease trials
EMA Guideline on the clinical investigation of medicines for the treatment of Alzheimer's diseaseGold-standard dementia staging instrument.
CDR-SB as cognitive/functional endpoint for early AD
EMA AD Guideline